The present invention relates to a novel use of piperine, more specifically, to a pharmaceutical or food composition containing the piperine or a pharmaceutically acceptable salt thereof as an active ingredient for preventing and treating obesity.Applications of piperine Piperine has diverse biological and therapeutic activities. It can dramatically increase the absorption of selenium, vitamin B and carotene as well as other nutrients [36. It can stimulate pancreatic and intestinal digestive enzymes and also increases biliary bile acid secretion when orally administrated [37. application of piperine
Piperine Background and Benefits. Piperine is an alkaloid that gives black pepper (Piper nigrum) its pungency. It is slightly soluble in water and highly soluble in alcohol, chloroform and ether. Piperine has a long history of use in some types of traditional medicine. Its primary commercial use is in modern herbal medicine.
For the preparation of the curcumin and piperine loaded zeinchitosan nanoparticles the first solution of zein and curcumin as an inner fluid for the core and the second solution of piperine and chitosan as an outer fluid for the shell of the nanoparticles have to be prepared. For that purpose the piperine concentration obtained from the extraction Wang YM, Lin W, Chai SC, Wu J, Ong SS, Schuetz EG, Chen T: Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1. Toxicol Appl Pharmacol. 2013 Oct 1; 272(1): . doi:application of piperine Research of the use of piperine for the treatment of vitiligo Piperine a novel treatment for vitiligo? Piperine is the main component of the commonly used spice, black pepper. Dr Amala Soumyanath (formerly Amala Raman) and her research group at Kings College London were excited to discover that piperine can make pigment cells divide.
Therefore, the application of piperine supplement at low dose to improve the brain function should be considered. In conclusion, piperine possesses antidepression like activity and cognitive enhancing effect, therefore, piperine especially at low dose is the potential alternative strategies to improve brain function. application of piperine Piperine, along with its isomer chavicine, is the alkaloid responsible for the pungency of black pepper and long pepper. It has been used in some forms of traditional medicine.